The applications of surgical sealants, glues and wound closure are many and are rapidly multiplying as more credible data is generated on each application and as physicians gain comfort in working with the products in routine clinical practice.
Below is a sample of surgical sealants, glues and wound closure applications by clinical area:
Source: MedMarket Diligence, LLC; [...]
Below are select technologies under development at recently identified medtechs startups:
Scaffold for regeneration of functional bone tissues.
Autologous, adipose-derived stem cells for treatment of traumatic brain injury and chronic obstructive pulmonary disease.
Device company developing technologies to improve the safety and efficiency of chemotherapy.
Developing stem cell therapies.
Devices to locate and protect nerves during surgery.
Minimally invasive (endoscopic) spine [...]
Fibrin and other medical/surgical sealants have developed a broad repertoire of applications supported by their utility addressing different wound and tissue types.
Below is a sampling of applications of fibrin and other sealants:
Local hemostatic measures for both surgical and trauma cases
Surgery in patients with bleeding disorders (e.g., hemophilia, severe thrombocytopenia) and non-bleeding cases with suspected fluid [...]
Translation: Drug-eluting stents are to bare metal stents as bare metal stents were to percutaneous transluminal coronary angioplasty alone.
In the September 1 post on the meta-analysis by researchers at Tuft Medical Center, we noted the overall findings in general terms of the value of drug-eluting stents compared to bare metal stents. It is worthwhile to provide [...]
The global market for medical devices is $200 billion opportunity and at least 13% of this market involves products that provide the controlled application of energy to tissue. The segment is dominated by high technology products ranging from devices that can heat and cool tissue over a 600° C temperature range of -200° C to [...]
High-strength glue products were approved for topical closure applications in the United States in the late 1990s. Outside the United States, high-strength glues and adhesives have been approved in some countries for a number of years and have built up a track record of use in internal surgery. With time, high-strength glues will come to [...]
In cardiovascular and spine surgery, multi-billion dollar markets were created from entirely new procedures between 1980 and 2000, with subsequent segmentation in later years particularly as new minimally invasive procedures were developed towards the end of the 20th century. In the cardiovascular arena, the development of new procedures for angioplasty and bypasses in the late [...]
Healthcare is viewed conventionally as being inelastic to economic downturns, since healthcare needs are independent of economic variables. But with the extent of the current recession reaching into credit availability, those medtech companies with short term financing needs – seed stage or startups, early stage, and developmental stage – have clearly depressed economic immunity. But [...]
Surgical management of soft tissues via "ablation" therapies, in which alternative energy types (radiation, electrosurgcal, ultrasound, etc.) are applied to excise, destroy, or otherwise produce a therapeutic effect at the tissue level has undergone a proliferation in development with all of these alternatives vying for caseload in clinical applications as diverse as tumor ablation, arrhythmia [...]
Treatment of coronary artery disease has become a sort of living laboratory for the evaluation of an incredible range of alternatives. Put simply, the options for patients fall generally to either a coronary artery bypass graft procedure to simply reroute new graft plumbing around the old, clogged pipes, or revascularizing the clogged arteries via a [...]
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