New technologies at medtech startups

2010

June/July

• Undisclosed orthopedic device technology.
• Less invasive pericardial access for treatment of cardiac arrhythmia.
• Medical technology company
• Surgical instrumentation
• Laser technology applied to tissue closure, other applications.
• Minimally invasive surgical technology

May

• Single incision laparoscopic surgery and natural orifice transluminal endoscopic surgery.
• Medical device development company.
• Surgical instrumentation and osteogenic biomaterials for spine surgery.
• Clinical diagnostics including a noninvasive prenatal diagnostics.
• Laparoscopic surgical instrumentation.
• Ultrasonic breast cancer detection device.
• Technologies for tendon, ligament and soft tissue repair.
• Cryogenic ablation system
• Bone fracture fixation.
• Laser ablation technologies via dynamic laser pulse system
• Intramedullary repair system for vertebra fractures

April

• Technologies in podiatry.
• Device for treatment of obstructive sleep apnea
• Device treatment of osteoarthritis.
• Device for revascularization of occlusions.
• Device to stabilize the spinal disc as treatment for degenerative disc disease.
• Developing implantable device for treatment of gastroesophageal reflux disease (GERD).
• Medical devices to improve the safety and efficiency of laparoscopic surgery.
• Tools for less invasive spinal surgery.
• Devices for spine surgery.
• Pedicle screw augmentation in the osteoporotic spine.
• Coronary stent technologies.

March/February

• Novel optical scalpel for ultra-precise ophthalmic laser surgery
• Wound healing technology based on choroid plexus proteins.
• Osteobiologics
• Creating "natural bionanomatrix coating technologies for medical devices and clinical problems in cardiovascular disease."
• Needleless vascular access for dialysis
• Stem cell coatings for medical devices and implants.
• Neuromodulation for urinary incontinence.
• Motion preservation and percutaneous technologies in spine surgery.
• New platform technology for vials, syringes, autoinjectors and other drug delivery devices.
• Dissolution of arterial plaques via elevation of bile salts.
• Developing an innovative ultrasound platform technology for medical applications.
• Laparoscopic instrument for repair of ventral hernias.
• Catheter-based drug delivery for treatmetn of vascular disease and restenosis.
• Late stage medical device acquisitions.

January

• Incubator company from shifamed.com
• Developing minimally invasive therapies for end stage renal disease.
• Electrical stimulation technology to restore temporary continence control for patients with colostomies.
• Sonolysis for treatment of vascular thromobus disorders.
• Undisclosed nanotech medical product development
• Medical robotics
• Undisclosed medical technology
• Tissue welding via cold plasma and albumin.
• Intravascular medical device coatings containing resveratrol and quercetin
• Collagen-based implants for soft tissue defects.
• Drug-device combinations in cardiovascular, renal and GI
• Endometrial ablation for treatment of abnormal uterine bleeding

2009

December

• Disposable microchip for handheld (point-of-care) diagnostics.
• Vascular access device.
• Technologies to treat pulmonary diseases.
• Medical device company focused on metabolic disorders.
• Surgical suture system.
• Biologically based nanomatrix coating technologies for medical devices.
• Ultrasound tissue ablation technology to non-invasively destroy tumors and other lesions.
• Ultrasound-based brain stimulation device for Parkinson's, Alzheimer’s disease, epilepsy, tinnitus, obsessive-compulsive disorder, obesity and chronic pain.

November

• Scaffold for regeneration of functional bone tissues.
• Autologous, adipose-derived stem cells for treatment of traumatic brain injury and chronic obstructive pulmonary disease.
• Device company developing technologies to improve the safety and efficiency of chemotherapy.
• Developing stem cell therapies.
• Devices to locate and protect nerves during surgery.
• Minimally invasive (endoscopic) spine surgery products.
• Technologies developed by physicians at a major hospital in a range of areas including imaging, cath lab procedures, fecal incontinence treatment, and others.
• Robotic system to assist in guidewire procedures.
• Nanoparticles to stimulate axon regeneration in spinal cord injury.

October

• Diagnostic imaging in urology and oncology.
• Endoscopic tissue management technology.
• Esophageal monitoring device to replace peripheral artery catheter.
• Products for treatment of fecal incontinence and GERD.
• Surgical instrumentation to reduce trauma of surgery.
• Suction device for use in sleep breathing disorders.
• Fully absorbable coronary stent.
• Drug-eluting balloons.

September

• Medical devices to enable deployment of vascular implants
• Tibial prosthesis
• Tools for performing less invasive orthopedic joint procedures.
• Technologies in in vitro fertilization (IVF)
• Medical device company developing antimicrobial materials for treatment of infections disease.
• Minimally invasive device technologies.
• Extracellular matrices for soft tissue regeneration.
• Portable home hemodialysis.
• Intravenously placed electrodes to stimulate the diaphragm as replacement for traditional mechanical ventilation.
• Photonic based surgical technologies platform.

August

• Finger-mounted ultrasound probe.
• Diagnostic and medical device technologies.
• Device to increase cerebral blood flow in stroke, Alzheimer's and other conditions.
• Device for the treatment of bowel incontinence. (A Shalon Ventures portfolio company.)
• Endoscopic treatment for gastric reflux.RF ablation technology for aesthetic applications.
• Stealth company developing non-spine orthopedic technology

July

• Pedicle screw replacement in spine surgery
• Transcatheter treatment of patent foramen ovale and septal defect.
• Soft tissue fixation technologies to improve the strength and simplicity of the reattachment of soft tissue to bone.
• Interventional devices for treating GI disorders (fistula closure).
• Developing for the delivery of epidural anaesthesia.
• Technology to improve the performance of vascular prostheses; initial application in abdominal aortic aneurysms (AAA).
• Minimally invasive implant for the treatment of stress incontinence.
• Novel vena caval filter for preventing pulmonary embolism.
• Spinal tension band for restriction of motion between vertebrae in spine disorders.
• Hydrogels for radiation oncology and cancer surgery indications.
• Undisclosed technology
• Undisclosed cardiac valve technology.

June

• Device for the prevention of migration and leakage problems associated with endovascular stent grafts for abdominal aortic aneurysms.
• Drug delivery technologies for treatment of vascular disease.
• R&D of spinal products
• System for detecting endothelial dysfunction as a precursor to cardiovascular disease.
• Implantable medical device for the treatment of benign prostate hyperplasia.
• Stent placement system
• Device for treatment of fractures of the neck of the femur.
• Develops devices embedded with stem-cell for treatment of acute organ failure.
• Drug-device products for localized drug delivery.

May

• Therapeutic cardiovascular devices.

• Catheter technologies.

• Undisclosed medical devices.

• Orthopedic attachment and fixation.

• Orthopedic joints (hip, knee, shoulder), fracture fixation and other devices.

• Electromechanical orthopedic implant to alleviate leg and lumbar pain.

• Percutaneous mitral valve replacement.

• Femtosecond lasers for cataract surgery

April

• Intraarterial ventricular assist device.

• Micro-robotic imaging and surgical device technology to facilitate minimally invasive surgeries.

• "Cell bandage" technology for repair of damaged knee meniscus.

• Glucose sensor and regulation technology

March

• External fixation for leg bone fractures.

• Devices for minimally invasive spine surgery

• Device for tissue preservation during orthopedic surgery

• Nanoparticle-based immunomodulatory drugs.

• Pharmaceutical preparations for treatment of obesity.

• Drug-eluting balloons.

• Implantable shunt for draining fluid, such as for synovial fluid.

• Undisclosed ophthalmic devices.

• Proprietary system to assist orthopedic surgeons in the delivery of long bone intramedullary nail implants.

• Devices in interventional cardiology.

• Coronary artery augmentation system to prevent need for reoperation of clotted grafts.

• Bio prosthetic devices including cardiovascular stents.

February

• Seed stage company within VC firm developing a low profile stent graft for the treatment of abdominal aortic aneurysms (AAA).

• Stealth medical device company

• Soft tissue regeneration of the anterior cruciate ligament (ACL) of the knee.

• Near infrared-based venous imaging system\embolic protection device

• Bioactive, polymer materials and coatings for medical devices to improve biocompatibility, safety, and improve MRI compatibility.

Dec/Jan

• Orthopedic implants to aid in fracture repair.

• Radio-frequency surgical applications in orthopedics.

• Autologous fluid concentrator

• Intraoperative nerve location and protection device.

• Peripheral nerve stimulation for treatment of post-stroke shoulder pain.

• Biocompatible, thermoplastic materials for osteosynthesis

• Pain management

• Minimally invasive spine technologies

• Novel treatments for gastrointestinal disorders.

• Innovative treatment for patients with osteoarthritis.

• Image-guided laparoscopy system

• Orthopedic implants

• Provider of products for the orthopaedic device market, formed via merger

• Developing device to diagnose abnormal joint conditions via ultrasound.

• Intraoperative nerve location and protection device

• Medical device to prevent surgical site infections in orthopedic and spinal surgeries

• Surgical dressings

• Spinal implant manufacturer

• Surgical irrigation and retraction systems

• Autologous fluid concentrator

• Nanotechnology biomaterials company developing angiogenic materials for use in wound management, treatment of ischemic heart disease, others

• Devices based on piezoelectric, magnetorestrictive and shape memory materials technologies, including a sonicator and an ophthalmic surgical device

• Medical device company backed by Flagship Ventures, Polaris Venture Partners and Third Rock Ventures

• Peripheral nerve stimulation for treatment of post-stroke shoulder pain

• Polymer-based absorbable surgical hemostats

2008

November

• Biomaterials for use in aesthetic surgery

• New vascular devices for use on patients that undergo procedures with a high risk of blood vessel blockage

• Treatments and diagnostics for orthopedics

• Devices for cardiac surgery, including a device for performing structured sternal incisions

• Handheld diagnostic device detecting cancer cells via fluorescing enzyme, performed following tumor removal to detect residual cancer

• Ambulatory cardiac monitoring

• Minimally invasive RF tissue welding technology for use in lung resection and biopsy

• Innovative technologies to treat heart valve disease

• Imaging capsule long-term monitoring of bladder cancer

October

• Laser devices to "weld" biological tissues together for wound closures.

• Drug-coated urinary and other catheters and stents that are designed to prevent or treat scar tissue.

• Artificial heart technologies.

• Heart pumps.

• Compliant balloon technologies.

• Device for mitral valve repair without need for sternotomy.

• Pharmaceutical treatments for ischemia and vascular disease, focused on peripheral artery disease.

• Non-polymeric drug eluting stent

• Device technology in diabetes management.

• Medical device inflatables, including devices for biological navigation such as in support of colonoscopy and other endoscopy.

• Minimally invasive products for motion-preserving spine surgery.

• Minimally invasive treatment of vertebral compression fractures.

• Minimally invasive treatments for removing varicose veins.

• Drug-coated angioplasty for coronary and peripheral applications

• Fully implantable artificial heart

September

• Recombinant proteins and cells for inter vertebral disc cell regeneration

• Non-hydrogel polymer used to stimulate tissue growth in dental/orthopedic applications

• Biomaterials and biologics for repair of bone and cartilage

• Portable endoscopic imaging

• Device treatments for restless leg syndrome (RLS)

• Disposable steerable surgical instrumentation for arthroscopy

• Technologies to restore spinal disc function

• Embolic protection system

(more archived startup technologies to be listed soon)

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